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  1. Ahner A, Gong X, Frizzell RA. Cystic fibrosis transmembrane conductance regulator degradation: cross-talk between the ubiquitylation and SUMOylation pathways. FEBS J. 2013 Sep;280(18):4430-8. PubMed PMID: 23809253; NIHMSID: 621868.
  2. Bahl CD, Hvorecny KL, Bridges AA, Ballok AE, Bomberger JM, Cady KC, O'Toole GA, Madden DR. Signature motifs identify an Acinetobacter Cif virulence factor with epoxide hydrolase activity. J Biol Chem. 2014 Mar 14;289(11):7460-9. PubMed PMID: 24474692; PubMed Central PMCID: PMC3953260.
  3. Bomberger JM, Coutermarsh BA, Barnaby RL, Sato JD, Chapline MC, Stanton BA. Serum and glucocorticoid-inducible kinase1 increases plasma membrane wt-CFTR in human airway epithelial cells by inhibiting its endocytic retrieval. PLoS One. 2014;9(2):e89599. PubMed PMID: 24586903; PubMed Central PMCID: PMC3931797.
  4. Bomberger JM, Ely KH, Bangia N, Ye S, Green KA, Green WR, Enelow RI, Stanton BA. Pseudomonas aeruginosa Cif protein enhances the ubiquitination and proteasomal degradation of the transporter associated with antigen processing (TAP) and reduces major histocompatibility complex (MHC) class I antigen presentation. J Biol Chem. 2014 Jan 3;289(1):152-62. PubMed PMID: 24247241; PubMed Central PMCID: PMC3879540.
  5. Bozoky Z, Krzeminski M, Muhandiram R, Birtley JR, Al-Zahrani A, Thomas PJ, Frizzell RA, Ford RC, Forman-Kay JD. Regulatory R region of the CFTR chloride channel is a dynamic integrator of phospho-dependent intra- and intermolecular interactions. Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):E4427-36. PubMed PMID: 24191035; PubMed Central PMCID: PMC3839774.
  6. Brodsky JL. The threads that tie protein-folding diseases. Dis Model Mech. 2014 Jan;7(1):3-4. PubMed PMID: 24396147; PubMed Central PMCID: PMC3882041.
  7. Buck TM, Plavchak L, Roy A, Donnelly BF, Kashlan OB, Kleyman TR, Subramanya AR, Brodsky JL. The Lhs1/GRP170 chaperones facilitate the endoplasmic reticulum-associated degradation of the epithelial sodium channel. J Biol Chem. 2013 Jun 21;288(25):18366-80. PubMed PMID: 23645669; PubMed Central PMCID: PMC3689978.
  8. Butterworth MB, Zhang L, Heidrich EM, Myerburg MM, Thibodeau PH. Activation of the epithelial sodium channel (ENaC) by the alkaline protease from Pseudomonas aeruginosa. J Biol Chem. 2012 Sep 21;287(39):32556-65. PubMed PMID: 22859302; PubMed Central PMCID: PMC3463336. Cascio S, Farkas AM, Hughey RP, Finn OJ. Altered glycosylation of MUC1 influences its association with CIN85: the role of this novel complex in cancer cell invasion and migration. Oncotarget. 2013 Oct;4(10):1686-97. PubMed PMID: 24072600; PubMed Central PMCID: PMC3858555.
  9. Chen J, Kleyman TR, Sheng S. Deletion of a-subunit exon 11 of the epithelial Na+ channel reveals a regulatory module. Am J Physiol Renal Physiol. 2014 Mar 1;306(5):F561-7. PubMed PMID: 24402098; PubMed Central PMCID: PMC3949035.
  10. Chen K, Kolls JK. T cell-mediated host immune defenses in the lung. Annu Rev Immunol. 2013;31:605-33. PubMed PMID: 23516986; PubMed Central PMCID: PMC3912562..
  11. Cihil KM, Swiatecka-Urban A. The cell-based L-glutathione protection assays to study endocytosis and recycling of plasma membrane proteins. J Vis Exp. 2013 Dec 13;PubMed PMID: 24378656; PubMed Central PMCID: PMC4048355.
  12. Corcoran TE, Thomas KM, Brown S, Myerburg MM, Locke LW, Pilewski JM. Liquid hyper-absorption as a cause of increased DTPA clearance in the cystic fibrosis airway. EJNMMI Res. 2013 Feb 27;3(1):14. PubMed PMID: 23446051; PubMed Central PMCID: PMC3600668.
  13. Corcoran TE, Niven R, Verret W, Dilly S, Johnson BA. Lung deposition and pharmacokinetics of nebulized cyclosporine in lung transplant patients. J Aerosol Med Pulm Drug Deliv. 2014 Jun;27(3):178-84. PubMed PMID: 23668548; PubMed Central PMCID: PMC4088352.
  14. Deslouches B, Steckbeck JD, Craigo JK, Doi Y, Mietzner TA, Montelaro RC. Rational design of engineered cationic antimicrobial peptides consisting exclusively of arginine and tryptophan, and their activity against multidrug-resistant pathogens. Antimicrob Agents Chemother. 2013 Jun;57(6):2511-21. PubMed PMID: 23507278; PubMed Central PMCID: PMC3716171.
  15. Di YP, Tkach AV, Yanamala N, Stanley S, Gao S, Shurin MR, Kisin ER, Kagan VE, Shvedova A. Dual acute proinflammatory and antifibrotic pulmonary effects of short palate, lung, and nasal epithelium clone-1 after exposure to carbon nanotubes. Am J Respir Cell Mol Biol. 2013 Nov;49(5):759-67. PubMed PMID: 23721177; PubMed Central PMCID: PMC3931096.
  16. Edinger RS, Bertrand CA, Rondandino C, Apodaca GA, Johnson JP, Butterworth MB. The epithelial sodium channel (ENaC) establishes a trafficking vesicle pool responsible for its regulation. PLoS One. 2012;7(9):e46593. PubMed PMID: 23029554; PubMed Central PMCID: PMC3460899.
  17. Gopal R, Rangel-Moreno J, Fallert Junecko BA, Mallon DJ, Chen K, Pociask DA, Connell TD, Reinhart TA, Alcorn JF, Ross TM, Kolls JK, Khader SA. Mucosal pre-exposure to Th17-inducing adjuvants exacerbates pathology after influenza infection. Am J Pathol. 2014 Jan;184(1):55-63. PubMed PMID: 24183780; PubMed Central PMCID: PMC3873493.
  18. Gruber W, Orenstein DM, Braumann KM, Beneke R. Interval exercise training in cystic fibrosis -- effects on exercise capacity in severely affected adults. J Cyst Fibros. 2014 Jan;13(1):86-91. PubMed PMID: 23863518.
  19. Guerriero CJ, Weiberth KF, Brodsky JL. Hsp70 targets a cytoplasmic quality control substrate to the San1p ubiquitin ligase. J Biol Chem. 2013 Jun 21;288(25):18506-20. PubMed PMID: 23653356; PubMed Central PMCID: PMC3689992.
  20. Happ MB, Hoffman LA, Higgins LW, Divirgilio D, Orenstein DM. Parent and child perceptions of a self-regulated, home-based exercise program for children with cystic fibrosis. Nurs Res. 2013 Sep- Oct;62(5):305-14. PubMed PMID: 23995464; PubMed Central PMCID: PMC4053557.
  21. Hendricks MR, Bomberger JM. Who's really in control: microbial regulation of protein trafficking in the epithelium. Am J Physiol Cell Physiol. 2014 Feb 1;306(3):C187-97. PubMed PMID: 24133062; PubMed Central PMCID: PMC3919996.
  22. Higgins LW, Robertson RJ, Kelsey SF, Olson MB, Hoffman LA, Rebovich PJ, Haile L, Orenstein DM. Exercise intensity self-regulation using the OMNI scale in children with cystic fibrosis. Pediatr Pulmonol. 2013 May;48(5):497-505. PubMed PMID: 22997144; PubMed Central PMCID: PMC3541455.
  23. Holleran JP, Zeng J, Frizzell RA, Watkins SC. Regulated recycling of mutant CFTR is partially restored by pharmacological treatment. J Cell Sci. 2013 Jun 15;126(Pt 12):2692-703. PubMed PMID: 23572510; PubMed Central PMCID: PMC3687701.
  24. Kang Y, Taldone T, Patel HJ, Patel PD, Rodina A, Gozman A, Maharaj R, Clement CC, Patel MR, Brodsky JL, Young JC, Chiosis G. Heat shock protein 70 inhibitors 1 2,5'-thiodipyrimidine and 5- (phenylthio)pyrimidine acrylamides as irreversible binders to an allosteric site on heat shock protein 70. J Med Chem. 2014 Feb 27;57(4):1188-207. PubMed PMID: 24548207; PubMed Central PMCID: PMC3983365.
  25. Klinkenberg D, Long KR, Shome K, Watkins SC, Aridor M. A cascade of ER exit site assembly that is regulated by p125A and lipid signals. J Cell Sci. 2014 Apr 15;127(Pt 8):1765-78. PubMed PMID: 24522181; PubMed Central PMCID: PMC3986675.
  26. Kuhlmann AS, Steckbeck JD, Sturgeon TJ, Craigo JK, Montelaro RC. Unique functional properties of conserved arginine residues in the lentivirus lytic peptide domains of the C-terminal tail of HIV-1 gp41. J Biol Chem. 2014 Mar 14;289(11):7630-40. PubMed PMID: 24497632; PubMed Central PMCID: PMC3953275.
  27. Kumar P, Chen K, Kolls JK. Th17 cell based vaccines in mucosal immunity. Curr Opin Immunol. 2013 Jun;25(3):373-80. PubMed PMID: 23669353; PubMed Central PMCID: PMC3721632.
  28. Liu Y, Bartlett JA, Di ME, Bomberger JM, Chan YR, Gakhar L, Mallampalli RK, McCray PB Jr, Di YP. SPLUNC1/BPIFA1 contributes to pulmonary host defense against Klebsiella pneumoniae respiratory infection. Am J Pathol. 2013 May;182(5):1519-31. PubMed PMID: 23499554; PubMed Central PMCID: PMC3644735.
  29. Liu Y, Di ME, Chu HW, Liu X, Wang L, Wenzel S, Di YP. Increased susceptibility to pulmonary Pseudomonas infection in Splunc1 knockout mice. J Immunol. 2013 Oct 15;191(8):4259-68. PubMed PMID: 24048904; PubMed Central PMCID: PMC3839417.
  30. Manni ML, Robinson KM, Alcorn JF. A tale of two cytokines: IL-17 and IL-22 in asthma and infection. Expert Rev Respir Med. 2014 Feb;8(1):25-42. PubMed PMID: 24325586; PubMed Central PMCID: PMC4123209.
  31. Martin RA, Ather JL, Daggett R, Hoyt L, Alcorn JF, Suratt BT, Weiss DJ, Lundblad LK, Poynter ME. The endogenous Th17 response in NO2-promoted allergic airway disease is dispensable for airway hyperresponsiveness and distinct from Th17 adoptive transfer. PLoS One. 2013;8(9):e74730. PubMed PMID: 24069338; PubMed Central PMCID: PMC3778003.
  32. McHugh KJ, Mandalapu S, Kolls JK, Ross TM, Alcorn JF. A novel outbred mouse model of 2009 pandemic influenza and bacterial coinfection severity. PLoS One. 2013;8(12):e82865. PubMed PMID: 24324838; PubMed Central PMCID: PMC3855784.
  33. Nakatsukasa K, Brodsky JL, Kamura T. A stalled retrotranslocation complex reveals physical linkage between substrate recognition and proteasomal degradation during ER-associated degradation. Mol Biol Cell. 2013 Jun;24(11):1765-75, S1-8. PubMed PMID: 23536702; PubMed Central PMCID: PMC3667728.
  34. Needham PG, Brodsky JL. How early studies on secreted and membrane protein quality control gave rise to the ER associated degradation (ERAD) pathway: the early history of ERAD. Biochim Biophys Acta. 2013 Nov;1833(11):2447-57. PubMed PMID: 23557783; PubMed Central PMCID: PMC3723753.
  35. Nguyen NL, Chen K, McAleer J, Kolls JK. Vitamin D regulation of OX40 ligand in immune responses to Aspergillus fumigatus. Infect Immun. 2013 May;81(5):1510-9. PubMed PMID: 23439304; PubMed Central PMCID: PMC3647994.
  36. Oriss TB, Krishnamoorthy N, Ray P, Ray A. Dendritic cell c-kit signaling and adaptive immunity: implications for the upper airways. Curr Opin Allergy Clin Immunol. 2014 Feb;14(1):7-12. PubMed PMID: 24300419; PubMed Central PMCID: PMC4125121.
  37. Paranjape SM, Lauer TW, Montelaro RC, Mietzner TA, Vij N. Modulation of proinflammatory activity by the engineered cationic antimicrobial peptide WLBU-2. F1000Res. 2013;2:36. PubMed PMID: 24555033; PubMed Central PMCID: PMC3894802.
  38. Pociask DA, Scheller EV, Mandalapu S, McHugh KJ, Enelow RI, Fattman CL, Kolls JK, Alcorn JF. IL-22 is essential for lung epithelial repair following influenza infection. Am J Pathol. 2013 Apr;182(4):1286-96. PubMed PMID: 23490254; PubMed Central PMCID: PMC3620404.
  39. Rasgado-Flores H, Krishna Mandava V, Siman H, Van Driessche W, Pilewski JM, Randell SH, Bridges RJ. Effect of apical hyperosmotic sodium challenge and amiloride on sodium transport in human bronchial epithelial cells from cystic fibrosis donors. Am J Physiol Cell Physiol. 2013 Dec 1;305(11):C1114-22. PubMed PMID: 23986197; PubMed Central PMCID: PMC3882386.
  40. Ray A, Chakraborty K, Ray P. Immunosuppressive MDSCs induced by TLR signaling during infection and role in resolution of inflammation. Front Cell Infect Microbiol. 2013;3:52. PubMed PMID: 24066282; PubMed Central PMCID: PMC3776133.
  41. Razawi H, Kinlough CL, Staubach S, Poland PA, Rbaibi Y, Weisz OA, Hughey RP, Hanisch FG. Evidence for core 2 to core 1 O-glycan remodeling during the recycling of MUC1. Glycobiology. 2013 Aug;23(8):935-45. PubMed PMID: 23640779; PubMed Central PMCID: PMC3695752.
  42. Robinson KM, Alcorn JF. T-cell immunotherapy in cystic fibrosis:weighing the risk/reward. Am J Respir Crit Care Med. 2013 Mar 15;187(6):564-6. PubMed PMID: 23504359.
  43. Robinson KM, Choi SM, McHugh KJ, Mandalapu S, Enelow RI, Kolls JK, Alcorn JF. Influenza A exacerbates Staphylococcus aureus pneumonia by attenuating IL-1▀ production in mice. J Immunol. 2013 Nov 15;191(10):5153-9. PubMed PMID: 24089191; PubMed Central PMCID: PMC3827735.
  44. Robinson KM, McHugh KJ, Mandalapu S, Clay ME, Lee B, Scheller EV, Enelow RI, Chan YR, Kolls JK, Alcorn JF. Influenza A virus exacerbates Staphylococcus aureus pneumonia in mice by attenuating antimicrobial peptide production. J Infect Dis. 2014 Mar;209(6):865-75. PubMed PMID: 24072844; PubMed Central PMCID: PMC3935471.
  45. Rosas-Salazar C, Walczak SA, Winger DG, Kurland G, Spahr JE. Comparison of two aspiration techniques of bronchoalveolar lavage in children. Pediatr Pulmonol. 2013 Oct 24;PubMed PMID: 24155175; PubMed Central PMCID: PMC3999312. [Epub ahead of print]
  46. Rowe SM, Liu B, Hill A, Hathorne H, Cohen M, Beamer JR, Accurso FJ, Dong Q, Ordo˝ez CL, Stone AJ, Olson ER, Clancy JP, VX06-770-101 Study Group. Optimizing nasal potential difference analysis for CFTR modulator development: assessment of ivacaftor in CF subjects with the G551D-CFTR mutation. PLoS One. 2013;8(7):e66955. PubMed PMID: 23922647; PubMed Central PMCID: PMC3724869.
  47. Sharma R, Corcoran TE, Garoff S, Przybycien TM, Swanson ER, Tilton RD. Quasi-immiscible spreading of aqueous surfactant solutions on entangled aqueous polymer solution subphases. ACS Appl Mater Interfaces. 2013 Jun 26;5(12):5542-9. PubMed PMID: 23705869; PubMed Central PMCID: PMC3959907.
  48. Shi S, Carattino MD, Hughey RP, Kleyman TR. ENaC regulation by proteases and shear stress. Curr Mol Pharmacol. 2013 Mar;6(1):28- 34. PubMed PMID: 23547932; PubMed Central PMCID: PMC3697921.
  49. Shi S, Kleyman TR. Gamma subunit second transmembrane domain contributes to epithelial sodium channel gating and amiloride block. Am J Physiol Renal Physiol. 2013 Dec 1;305(11):F1585-92. PubMed PMID: 24107424; PubMed Central PMCID: PMC3882368.
  50. Snodgrass SM, Cihil KM, Cornuet PK, Myerburg MM, Swiatecka-Urban A. Tgf-▀1 inhibits Cftr biogenesis and prevents functional rescue of ?F508-Cftr in primary differentiated human bronchial epithelial cells. PLoS One. 2013;8(5):e63167. PubMed PMID: 23671668; PubMed Central PMCID: PMC3650079.
  51. Steckbeck JD, Deslouches B, Montelaro RC. Antimicrobial peptides: new drugs for bad bugs?. Expert Opin Biol Ther. 2014 Jan;14(1):11-4. PubMed PMID: 24206062; PubMed Central PMCID: PMC4109705.
  52. Szent-Gyorgyi C, Stanfield RL, Andreko S, Dempsey A, Ahmed M, Capek S, Waggoner AS, Wilson IA, Bruchez MP. Malachite green mediates homodimerization of antibody VL domains to form a fluorescent ternary complex with singular symmetric interfaces. J Mol Biol. 2013 Nov 15;425(22):4595-613. PubMed PMID: 23978698; PubMed Central PMCID: PMC3919518.
  53. Thibodeau PH, Butterworth MB. Proteases, cystic fibrosis and the epithelial sodium channel (ENaC). Cell Tissue Res. 2013 Feb;351(2):309-23. PubMed PMID: 22729487.
  54. Tran JR, Brodsky JL. The Cdc48-Vms1 complex maintains 26S proteasome architecture. Biochem J. 2014 Mar 15;458(3):459-67. PubMed PMID: 24351022; PubMed Central PMCID: PMC4135392.
  55. Way EE, Chen K, Kolls JK. Dysregulation in lung immunity - the protective and pathologic Th17 response in infection. Eur J Immunol. 2013 Dec;43(12):3116-24. PubMed PMID: 24130019; PubMed Central PMCID: PMC3947216.
  56. Weixel KM, Marciszyn A, Alzamora R, Li H, Fischer O, Edinger RS, Hallows KR, Johnson JP. Resveratrol inhibits the epithelial sodium channel via phopshoinositides and AMP-activated protein kinase in kidney collecting duct cells. PLoS One. 2013;8(10):e78019. PubMed PMID: 24205069; PubMed Central PMCID: PMC3812018.
  57. Xu J, Chang J, Yan Q, Dertinger T, Bruchez M, Weiss S. Labeling Cytosolic Targets in Live Cells with Blinking Probes. J Phys Chem Lett. 2013 Jul 3;4(13):2138-2146. PubMed PMID: 23930154; PubMed Central PMCID: PMC3733402.
  58. Yan Q, Schwartz SL, Maji S, Huang F, Szent-Gyorgyi C, Lidke DS, Lidke KA, Bruchez MP. Localization microscopy using noncovalent fluorogen activation by genetically encoded fluorogen-activating proteins. Chemphyschem. 2014 Mar 17;15(4):687-95. PubMed PMID: 24194371; PubMed Central PMCID: PMC3967550.
 

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