The CFRC is comprised of 50 faculty members from ten departments, who provide research strengths in areas ranging from basic science to clinical investigations. Its members garner more than $13 M/yr in extramural grants and contracts to support our CF research efforts.

CFRC Funding Opportunities:

2023 CFRC Impact Grants  

We are pleased to announce a new round of Pilot and Feasibility Grants to be funded by the University of Pittsburgh Cystic Fibrosis (CF) Research Center (CFRC) starting in July 2023.  These grants are designed to attract new investigators, or established investigators with new ideas, to the CF research area.  They provide seed funds for the acquisition of data that will enable expanded applications to the NIH or the Cystic Fibrosis Foundation (CFF).  These proposals should be innovative, but also targeted to the mission of the CFF.  

Grants are funded for up to two years, and they have an upper funding limit of $50,000/yr. 

Research areas for this program should align with the research priorities described in the most recent strategic plan from the Cystic Fibrosis Foundation, which can be found here: https://www.cff.org/about-us/our-strategic-plan.

Applications must include:

• Budget (form attached) for 1 or 2 years
• NIH Biosketches for principal and co-investigators
• Specific Aims, Significance, including a paragraph describing relevance of the project to the mission of CFF, and Approach, not to exceed 3 pages

Dates and Deadlines:

Application Deadline:  May 12, 2023
Notification of Award: June 2, 2023
Funding starts:  July 1, 2023      

Investigators at the University of Pittsburgh and Carnegie Mellon University are eligible.

Both basic and translational research applications are welcome.

Questions?  Please contact Tim Corcoran (tec23@pitt.edu).

Applications should be submitted to Katie Nauman (naumanke@upmc.edu) by 5/12/23.

 

 

Current and Past Pilot/Feasibility Projects:

Pilot Start Date	PI	Department	Title of Pilot
June 1 2018	Vaughn Cooper	MMG	Response of the lung microbiome to commonly used inhaled antibiotics
October 1 2017	Carlos Camacho	Computational and Systems Biology	Discovering novel inhibitors of the E3 ubiquitin ligase CHIP using a rational gemonic/structure-based screen
June 1 2017	Alison Morris/Barbara Methé	Pulmonary	Microbiome-host interactions during cystic fibrosis pulmonary exaebations using multi-omics approaches
June 1 2016	Timothy Hand	Pediatrics	Role of immune response to the intestinal microbiota in Cystic Fibrosis
June 1 2015	John Alcorn	Pediatrics	The impact of CFTR dysfunction on epithelial host defense against S. aureus
June 1 2014	Agnes Urban	Pediatrics	LMTK2 and TGF Beta Signaling in Human Airway Epithelial Cells
June 1 2013	Marcel Bruchez	CMU-Biological Sciences	Discovery of New Gene Targets for CF Therapies
June 1 2012	Ronald Montelaro	MMG	Engineered Cationic antimicrobial peptides (eCAP) for the treatment of viral and bacterial respiratory infections in CF patients
June 1 2012	Xinyu Lio	Chemistry	Decode the Viculence Signaling Network of Pathogenic Bacteria in Cystic Fibrosis Lung Infection
June 1 2011	Thomas Gilbert	Surgery	Ex Vivo Model of Cystic Firbrosis
June 1 2011	Jennifer Bomberger	MMG	Pseudomonas-vial Co-infection in Cystic Fibrosis