Funding

The CFRC is comprised of 50 faculty members from ten departments, who provide research strengths in areas ranging from basic science to clinical investigations. Its members garner more than $13 M/yr in extramural grants and contracts to support our CF research efforts.

The Center's program support is derived from core center grants from the NIH and Cystic Fibrosis Foundation that primarily support core facilities and Pilot/Feasibility (P/F) Projects:

  • NIH-NIDDK P30 DK072506-04 "Basic and Translational Studies of Cystic Fibrosis"
  • Cystic Fibrosis Foundation RDP:R883-CR07 "Cystic Fibrosis Research Development Program"

Research Funds Available:

The CFRC has offered P/F grants to attract new investigators to CF research since 1997. Applications for these grants are submitted on an annual cycle with review in late spring and potential funding July 1. New applications are solicited via University-wide mailings three months prior (April 1).

 

Current and Past Pilot/Fesability Projects:

Pilot Start Date

PI

Department

Title of Pilot

June 1 2018

Vaughn Cooper

MMG

Response of the lung microbiome to commonly used inhaled antibiotics

October 1 2017

Carlos Camacho

Computational and
Systems Biology

Discovering novel inhibitors of the E3 ubiquitin ligase CHIP using a rational gemonic/structure-based screen

June 1 2017

Allison Morris/Barbara Methe

Pulmonary

Microbiome-host interactions during cystic fibrosis pulmonary exaebations using multi-omics approaches

June 1 2016

Timothy Hand

Pediatrics

Role of immune response to the intestinal microbiota in Cystic Fibrosis

June 1 2015

John Alcorn

Pediatrics

The impact of CFTR dysfunction on epithelial host defense against S. aureus

June 1 2014

Agnes Urban

Pediatrics

LMTK2 and TGF Beta Signaling in Human Airway Epithelial Cells

June 1 2013

Marcel Bruchez

CMU-Biological Sciences

Discovery of New Gene Targets for CF Therapies

June 1 2012

Ronald Montelaro

MMG

Engineered Cationic antimicrobial peptides (eCAP) for the treatment of viral and bacterial respiratory infections in CF patients

June 1 2012

Xinyu Lio

Chemistry

Decode the Viculence Signaling Network of Pathogenic Bacteria in Cystic Fibrosis Lung Infection

June 1 2011

Thomas Gilbert

Surgery

Ex Vivo Model of Cystic Firbrosis

June 1 2011

Jennifer Bomberger

MMG

Pseudomanas-vial Co-infection in Cystic Fibrosis