Education & Training
- MD, University of Florida, 1981
- BS, University of Florida, 1978
Research Interest Summary
Research Interests
Dr. Wenzel is one of seven NHLBI funded investigators in the Severe Asthma Research Program (SARP) network and Co-directs a PO1 on severe asthma with her collaborator, Dr. Anuradha Ray. Through SARP and her own efforts, Dr. Wenzel has accumulated a clinical database of over 500 subjects with asthma and healthy controls, most of whom have matching airway tissue, cells and sputum/lavage. Her lab is one of few which is able to match an extensive clinical phenotype of a subject with responses at a cellular/molecular level. She is developing rich databases of gene expression in asthma. Her current bench-lab interests include the role of epithelial cells in controlling airway inflammatory responses, oxidative and nitrative stress, as well as their interactions with mast cells and Th1 immune responses.