2022

Donaldson SH, Laube BL, Mogayzel P, Corcoran TE, Pilewski JM, Ceppe A, Wu J, Bhambhvani PG, Ratjen F, Sagel SD, Clancy JP, Rowe SM, Bennett WD. Effect of lumacaftor-ivacaftor on mucociliary clearance and clinical outcomes in cystic fibrosis: Results from the PROSPECT MCC sub-study J Cyst Fibros. 2022 Jan;21(1):143-145. PMID: 34083123; PMCID: PMC8630086.

Hebestreit H, Kriemler S, Schindler C, Stein L, Karila C, Urquhart DS, Orenstein DM, Lands LC, Schaeff J, Eber E, Radtke T; ACTIVATE-CF Study Working Group. Effects of a Partially Supervised Conditioning Program in Cystic Fibrosis: An International Multicenter, Randomized Controlled Trial (ACTIVATE-CF) Am J Respir Crit Care Med. 2022 Feb 1;205(3):330-339.: 34735776; PMCID: PMC8887001.

 

2021

Armbruster CR, Marshall CW, Garber AI, Melvin JA, Zemke AC, Moore J, Zamora PF, Li K, Fritz IL, Manko CD, Weaver ML, Gaston JR, Morris A, Methé B, DePas WH, Lee SE, Cooper VS, Bomberger JM. Adaptation and genomic erosion in fragmented Pseudomonas aeruginosa populations in the sinuses of people with cystic fibrosis Cell Rep. 2021 Oct 19;37(3):109829. PMID: 34686349; PMCID: PMC8667756.

Corbera-Hincapie MA, Kurland KS, Hincapie MR, Fabio A, Weiner DJ, Kim SC, Kazmerski TM. Geospatial Analysis of Food Deserts and Their Impact on Health Outcomes in Children with Cystic Fibrosis Nutrients. 2021 Nov 10;13(11):3996. PMID: 34836250; PMCID: PMC8621515.

Kumar P, Soni DK, Sen C, Larsen MB, Mazan-Mamczarz K, Piao Y, De S, Gorospe M, Frizzell RA, Biswas R. SFPQ rescues F508del-CFTR expression and function in cystic fibrosis bronchial epithelial cells Sci Rep. 2021 Aug 17;11(1):16645. PMID: 34404863; PMCID: PMC8371023.

Larsen MB, Choi JJ, Wang X, Myerburg MM, Frizzell RA, Bertrand CA. Separating the contributions of SLC26A9 and CFTR to anion secretion in primary human bronchial epithelia Am J Physiol Lung Cell Mol Physiol. 2021 Dec 1;321(6):L1147-L1160. PMID: 34668421; PMCID: PMC8715023.

Shah P, Lowery E, Chaparro C, Visner G, Hempstead SE, Abraham J, Bhakta Z, Carroll M, Christon L, Danziger-Isakov L, Diamond JM, Lease E, Leonard J, Litvin M, Poole R, Vlahos F, Werchan C, Murray MA, Tallarico E, Faro A, Pilewski JM, Hachem RR. Cystic fibrosis foundation consensus statements for the care of cystic fibrosis lung transplant recipients J Heart Lung Transplant. 2021 Jul;40(7):539-556. PMID: 34103223.

Weinstock MS, Shaffer AD, Stapleton AL. Predictors of sinonasal disease onset, progression, and severity in pediatric cystic fibrosis patients Am J Otolaryngol. 2021 Sep-Oct;42(5):103016. PMID: 33836483; PMCID: PMC8403133.

 

2020

Armbruster CR, Coenye T, Touqui L, Bomberger JM. Interplay between host-microbe and microbe-microbe interactions in cystic fibrosis J Cyst Fibros. 2020 Mar;19 Suppl 1(Suppl 1):S47-S53. PMID: 31685398; PMCID: PMC7035965.

Kapnadak SG, Dimango E, Hadjiliadis D, Hempstead SE, Tallarico E, Pilewski JM, Faro A, Albright J, Benden C, Blair S, Dellon EP, Gochenour D, Michelson P, Moshiree B, Neuringer I, Riedy C, Schindler T, Singer LG, Young D, Vignola L, Zukosky J, Simon RH. Cystic Fibrosis Foundation consensus guidelines for the care of individuals with advanced cystic fibrosis lung disease J Cyst Fibros. 2020 May;19(3):344-354. PMID: 32115388; PMCID: .

Kidd KM, Sequeira GM, Voss RV, Weiner DJ, Ramsey BW, Jain R, Kazmerski TM. Caring for gender diverse youth with cystic fibrosis J Cyst Fibros. 2020 Nov;19(6):1018-1020. PMID: 32268993; PMCID: PMC8746999.

Okoniewski W, Hughan KS, Weiner GA, Weiner DJ, Forno E. Glycemic control and FEV(1) recovery during pulmonary exacerbations in pediatric cystic fibrosis-related diabetes J Cyst Fibros. 2020 May;19(3):460-465. PMID: 31980357; PMCID: PMC7329580.

Ramos KJ, Kapnadak SG, Bradford MC, Somayaji R, Morrell ED, Pilewski JM, Lease ED, Mulligan MS, Aitken ML, Gries CJ, Goss CH. Underweight Patients With Cystic Fibrosis Have Acceptable Survival Following Lung Transplantation: A United Network for Organ Sharing Registry Study Chest. 2020 Apr;157(4):898-906. PMID: 31958441; PMCID: PMC7118242.

Ramos KJ, Pilewski JM, Faro A, Marshall BC. Improved Prognosis in Cystic Fibrosis: Consideration for Intensive Care during the COVID-19 Pandemic Am J Respir Crit Care Med. 2020 Jun 1;201(11):1434-1435. PMID: 32289235; PMCID: PMC7258637.

Smith PJ, Dunitz JM, Lucy A, Hempstead SE, Tallarico E, Faro A, Pilewski JM, Ramos KJ. Incorporating patient and caregiver feedback into lung transplant referral guidelines for individuals with cystic fibrosis-Preliminary findings from a novel paradigm Clin Transplant. 2020 Oct;34(10):e14038. PMID: 32654238; PMCID: PMC7868110.

Trandel ET, Pilewski JM, Dellon EP, Jeong K, Yabes JG, Moreines LT, Arnold RM, Hoydich ZP, Kavalieratos D. Prevalence of unmet palliative care needs in adults with cystic fibrosis J Cyst Fibros. 2020 May;19(3):394-401. PMID: 31862306; PMCID: PMC8662333.

 

2019

Corcoran TE, Huber AS, Myerburg MM, Weiner DJ, Locke LW, Lacy RT, Weber L, Czachowski MR, Johnston DJ, Muthukrishnan A, Lennox AT, Pilewski JM. Multiprobe Nuclear Imaging of the Cystic Fibrosis Lung as a Biomarker of Therapeutic Effect J Aerosol Med Pulm Drug Deliv. 2019 Aug;32(4):242-249. PMID: 30969149; PMCID: PMC6685188.

Harano T, Haidar G, Schaheen L, Morrell MR, Pilewski JM, D'Cunha J. Successful lung transplantation from a hepatitis C RNA-positive donor to a hepatitis C treatment-experienced recipient with cystic fibrosis J Thorac Cardiovasc Surg. 2019 Oct;158(4):e155-e157. PMID: 31229293.

Kumar P, Sen C, Peters K, Frizzell RA, Biswas R. Comparative analyses of long non-coding RNA profiles in vivo in cystic fibrosis lung airway and parenchyma tissues Respir Res. 2019 Dec 16;20(1):284. PMID: 31842871; PMCID: PMC6916039.

Morrell MR, Kiel SC, Pilewski JM. Organ Transplantation for Cystic Fibrosis Semin Respir Crit Care Med. 2019 Dec;40(6):842-856. PMID: 31887769.

Ramos KJ, Smith PJ, McKone EF, Pilewski JM, Lucy A, Hempstead SE, Tallarico E, Faro A, Rosenbluth DB, Gray AL, Dunitz JM; CF Lung Transplant Referral Guidelines Committee. Lung transplant referral for individuals with cystic fibrosis: Cystic Fibrosis Foundation consensus guidelines J Cyst Fibros. 2019 May;18(3):321-333. PMID: 30926322; PMCID: PMC6545264.

Serrano Castillo F, Bertrand CA, Myerburg MM, Shapiro ME, Corcoran TE, Parker RS. A physiologically-motivated model of cystic fibrosis liquid and solute transport dynamics across primary human nasal epithelia J Pharmacokinet Pharmacodyn. 2019 Oct;46(5):457-472. PMID: 31494805.

Sun T, Sun Z, Jiang Y, Ferguson AA, Pilewski JM, Kolls JK, Chen W, Chen K. Transcriptomic Responses to Ivacaftor and Prediction of Ivacaftor Clinical Responsiveness Am J Respir Cell Mol Biol. 2019 Nov;61(5):643-652. PMID: 30995102; PMCID: PMC6827069.

Trandel ET, Pilewski JM, Dellon EP, Moreines LT, Yabes JG, Jeong K, Arnold RM, Kavalieratos D. Symptom Burden and Unmet Existential Needs in Adults With Cystic Fibrosis West J Nurs Res. 2019 Oct;41(10):1448-1464. PMID: 31267835.

Wolter DJ, Onchiri FM, Emerson J, Precit MR, Lee M, McNamara S, Nay L, Blackledge M, Uluer A, Orenstein DM, Mann M, Hoover W, Gibson RL, Burns JL, Hoffman LR; SCVSA study group. Prevalence and clinical associations of Staphylococcus aureus small-colony variant respiratory infection in children with cystic fibrosis (SCVSA): a multicentre, observational study Lancet Respir Med. 2019 Dec;7(12):1027-1038. PMID: 31727592; PMCID: PMC6924508.

Zemke AC, Nouraie SM, Moore J, Gaston JR, Rowan NR, Pilewski JM, Bomberger JM, Lee SE. Clinical predictors of cystic fibrosis chronic rhinosinusitis severity Int Forum Allergy Rhinol. 2019 Jul;9(7):759-765. PMID: 31162888; PMCID: PMC6715283.

 

2018

Abraham O, Li JS, Monangai KE, Feathers AM, Weiner D. The pharmacist's role in supporting people living with cystic fibrosis J Am Pharm Assoc (2003). 2018 May-Jun;58(3):246-249. PMID: 29459095.

Al Qatarneh S, Michel HK, Lindblad D, Ozolek J, Venkat V, Weiner DJ. Pancreatic Cystosis and Intrahepatic Biliopathy in a Young Adult with Cystic Fibrosis J Pediatr. 2018 Dec;203:457-457.e1. PMID: 30041939.

Dar HH, Tyurina YY, Mikulska-Ruminska K, Shrivastava I, Ting HC, Tyurin VA, Krieger J, St Croix CM, Watkins S, Bayir E, Mao G, Armbruster CR, Kapralov A, Wang H, Parsek MR, Anthonymuthu TS, Ogunsola AF, Flitter BA, Freedman CJ, Gaston JR, Holman TR, Pilewski JM, Greenberger JS, Mallampalli RK, Doi Y, Lee JS, Bahar I, Bomberger JM, Bayır H, Kagan VE. Pseudomonas aeruginosa utilizes host polyunsaturated phosphatidylethanolamines to trigger theft-ferroptosis in bronchial epithelium J Clin Invest. 2018 Oct 1;128(10):4639-4653. PMID: 30198910; PMCID: PMC6159971.

Donaldson SH, Laube BL, Corcoran TE, Bhambhvani P, Zeman K, Ceppe A, Zeitlin PL, Mogayzel PJ Jr, Boyle M, Locke LW, Myerburg MM, Pilewski JM, Flanagan B, Rowe SM, Bennett WD. Effect of ivacaftor on mucociliary clearance and clinical outcomes in cystic fibrosis patients with G551D-CFTR JCI Insight. 2018 Dec 20;3(24):e122695. PMID: 30568035; PMCID: PMC6338313.

Donaldson SH, Pilewski JM, Griese M, Cooke J, Viswanathan L, Tullis E, Davies JC, Lekstrom-Himes JA, Wang LT; VX11-661-101 Study Group. Tezacaftor/Ivacaftor in Subjects with Cystic Fibrosis and F508del/F508del-CFTR or F508del/G551D-CFTR Am J Respir Crit Care Med. 2018 Jan 15;197(2):214-224. PMID: 28930490; PMCID: PMC5768901.

Hebestreit H, Lands LC, Alarie N, Schaeff J, Karila C, Orenstein DM, Urquhart DS, Hulzebos EHJ, Stein L, Schindler C, Kriemler S, Radtke T; ACTIVATE-CF Study Working Group. Effects of a partially supervised conditioning programme in cystic fibrosis: an international multi-centre randomised controlled trial (ACTIVATE-CF): study protocol BMC Pulm Med. 2018 Feb 8;18(1):31. PMID: 29422091; PMCID: PMC5806352.

Kazmerski TM, Sawicki GS, Miller E, Jones KA, Abebe KZ, Tuchman LK, Ladores S, Rubenstein RC, Sagel SD, Weiner DJ, Pilewski JM, Orenstein DM, Borrero S. Sexual and reproductive health care utilization and preferences reported by young women with cystic fibrosis J Cyst Fibros. 2018 Jan;17(1):64-70. PMID: 28866451.

Kazmerski TM, Sawicki GS, Miller E, Jones KA, Abebe KZ, Tuchman LK, Ladores S, Rubenstein RC, Sagel SD, Weiner DJ, Pilewski JM, Orenstein DM, Borrero S. Sexual and reproductive health behaviors and experiences reported by young women with cystic fibrosis J Cyst Fibros. 2018 Jan;17(1):57-63. PMID: 28774749.

Kiedrowski MR, Gaston JR, Kocak BR, Coburn SL, Lee S, Pilewski JM, Myerburg MM, Bomberger JM. Staphylococcus aureus Biofilm Growth on Cystic Fibrosis Airway Epithelial Cells Is Enhanced during Respiratory Syncytial Virus Coinfection mSphere. 2018 Aug 15;3(4):e00341-18. PMID: 30111629; PMCID: PMC6094059.

Sagel SD, Khan U, Jain R, Graff G, Daines CL, Dunitz JM, Borowitz D, Orenstein DM, Abdulhamid I, Noe J, Clancy JP, Slovis B, Rock MJ, McCoy KS, Strausbaugh S, Livingston FR, Papas KA, Shaffer ML. Effects of an Antioxidant-enriched Multivitamin in Cystic Fibrosis. A Randomized, Controlled, Multicenter Clinical Trial Am J Respir Crit Care Med. 2018 Sep 1;198(5):639-647. PMID: 29688760; PMCID: PMC6118015.

Taylor-Cousar JL, Jain M, Barto TL, Haddad T, Atkinson J, Tian S, Tang R, Marigowda G, Waltz D, Pilewski J; VX14-809-106 Investigator Group. Lumacaftor/ivacaftor in patients with cystic fibrosis and advanced lung disease homozygous for F508del-CFTR J Cyst Fibros. 2018 Mar;17(2):228-235. PMID: 29126871.

 

2017

Lechtzin N, Mayer-Hamblett N, West NE, Allgood S, Wilhelm E, Khan U, Aitken ML, Ramsey BW, Boyle MP, Mogayzel PJ Jr, Gibson RL, Orenstein D, Milla C, Clancy JP, Antony V, Goss CH; eICE Study Team. Home Monitoring of Patients with Cystic Fibrosis to Identify and Treat Acute Pulmonary Exacerbations. eICE Study Results Am J Respir Crit Care Med. 2017 Nov 1;196(9):1144-1151. PMID: 28608719; PMCID: PMC5694835.

Kazmerski TM, Borrero S, Sawicki GS, Abebe KZ, Jones KA, Tuchman LK, Weiner DJ, Pilewski JM, Orenstein DM, Miller E. Provider Attitudes and Practices toward Sexual and Reproductive Health Care for Young Women with Cystic Fibrosis J Pediatr Adolesc Gynecol. 2017 Oct;30(5):546-552. PMID: 28163120.

Lee N, Le Sage V, Nanni AV, Snyder DJ, Cooper VS, Lakdawala SS. Genome-wide analysis of influenza viral RNA and nucleoprotein association. Nucleic Acids Res. 2017 Sep 6;45(15):8968-8977. PMID: 28911100; PMCID: PMC5587783.

Corcoran TE, Godovchik JE, Donn KH, Busick DR, Goralski J, Locke LW, Markovetz MR, Myerburg MM, Muthukrishnan A, Weber L, Lacy RT, Pilewski JM. Overnight delivery of hypertonic saline by nasal cannula aerosol for cystic fibrosis Pediatr Pulmonol. 2017 Sep;52(9):1142-1149. PMID: 28737262; PMCID: PMC5561478.

Stella NA, Callaghan JD, Zhang L, Brothers KM, Kowalski RP, Huang JJ, Thibodeau PH, Shanks RMQ. SlpE is a calcium-dependent cytotoxic metalloprotease associated with clinical isolates of Serratia marcescens. Res Microbiol. 2017 Jul-Aug;168(6):567-574. PMID: 28366837; PMCID: PMC5503780.

Freedman S, Orenstein D, Black P, Brown P, McCoy K, Stevens J, Grujic D, Clayton R. Increased Fat Absorption From Enteral Formula Through an In-line Digestive Cartridge in Patients With Cystic Fibrosis J Pediatr Gastroenterol Nutr. 2017 Jul;65(1):97-101. PMID: 28471913.

Guerriero CJ, Reutter KR, Augustine AA, Preston GM, Weiberth KF, Mackie TD, Cleveland-Rubeor HC, Bethel NP, Callenberg KM, Nakatsukasa K, Grabe M, Brodsky JL. Transmembrane helix hydrophobicity is an energetic barrier during the retrotranslocation of integral membrane ERAD substrates. Mol Biol Cell. 2017 Jul 15;28(15):2076-2090. PMID: 28539401; PMCID: PMC5509421.

Zhang H, Luo J, Alcorn JF, Chen K, Fan S, Pilewski J, Liu A, Chen W, Kolls JK, Wang J. AIM2 Inflammasome Is Critical for Influenza-Induced Lung Injury and Mortality. J Immunol. 2017 Jun 1;198(11):4383-4393. PMID: 28424239; PMCID: PMC5439025.

Bertrand CA, Mitra S, Mishra SK, Wang X, Zhao Y, Pilewski JM, Madden DR, Frizzell RA. The CFTR trafficking mutation F508del inhibits the constitutive activity of SLC26A9. Am J Physiol Lung Cell Mol Physiol. 2017 Jun 1;312(6):L912-L925. PMID: 28360110; PMCID: PMC5495941.

Sharma R, Corcoran TE, Garoff S, Przybycien TM, Tilton RD. Transport of a partially wetted particle at the liquid/vapor interface under the influence of an externally imposed surfactant generated Marangoni stress. Colloids Surf A Physicochem Eng Asp. 2017 May 20;521:49-60.: 28479673; PMCID: PMC5415349.

Pociask DA, Robinson KM, Chen K, McHugh KJ, Clay ME, Huang GT, Benos PV, Janssen-Heininger YMW, Kolls JK, Anathy V, Alcorn JF. Epigenetic and Transcriptomic Regulation of Lung Repair during Recovery from Influenza Infection. Am J Pathol. 2017 Apr;187(4):851-863. PMID: 28193481; PMCID: PMC5397680.

Rowan NR, Wang EW, Kanaan A, Sahu N, Williams JV, Phillips CD, Lee SE. Respiratory viral detection in the paranasal sinuses of patients with cystic fibrosis Am J Rhinol Allergy. 2017 Mar 1;31(2):105-108. PMID: 28452706.

Manni ML, Mandalapu S, Salmeron A, Lora JM, Kolls JK, Alcorn JF. Bromodomain and Extra-Terminal Protein Inhibition Attenuates Neutrophil-dominant Allergic Airway Disease. Scientific reports. 2017 February 24;7:43139. PMID: 28233801; PMCID: PMC5324049.

Wu T, Huang J, Moore PJ, Little MS, Walton WG, Fellner RC, Alexis NE, Peter Di Y, Redinbo MR, Tilley SL, Tarran R. Identification of BPIFA1/SPLUNC1 as an epithelium-derived smooth muscle relaxing factor. Nat Commun. 2017 Feb 6;8:14118. PMID: 28165446; PMCID: PMC5303822.

Chakraborty K, Raundhal M, Chen BB, Morse C, Tyurina YY, Khare A, Oriss TB, Huff R, Lee JS, St Croix CM, Watkins S, Mallampalli RK, Kagan VE, Ray A, Ray P. The mito-DAMP cardiolipin blocks IL-10 production causing persistent inflammation during bacterial pneumonia. Nat Commun. 2017 Jan 11;8:13944. PMID: 28074841 PMCID: PMC5241690.

Doll S, Proneth B, Tyurina YY, Panzilius E, Kobayashi S, Ingold I, Irmler M, Beckers J, Aichler M, Walch A, Prokisch H, Trümbach D, Mao G, Qu F, Bayir H, Füllekrug J, Scheel CH, Wurst W, Schick JA, Kagan VE, Angeli JP, Conrad M. ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition. Nat Chem Biol. 2017 Jan;13(1):91-98. PMID: 27842070; PMCID: PMC5610546.

Flitter BA, Hvorecny KL, Ono E, Eddens T, Yang J, Kwak DH, Bahl CD, Dolben E, Hampton T, Morisseau C, Hammock BD, Liu X, Hogan DA, Lee JS, Kolls JK, Levy BD, Madden DR, Bomberger JM. Pseudomonas aeruginosa sabotages the generation of host pro-resolving lipid mediators. Proc Natl Acad Sci U S A. 2017 Jan 3;114(1):136-141. PMID: 27980032 PMCID: PMC5224368.

Gopal R, Rapaka RR, Kolls JK. Immune reconstitution inflammatory syndrome associated with pulmonary pathogens. Eur Respir Rev. 2017 Jan 3;26(143):160042. PMID: 28049128; PMCID: PMC5642276.

Kagan VE, Bayır H, Tyurina YY, Bolevich SB, Maguire JJ, Fadeel B, Balasubramanian K. Elimination of the unnecessary: Intra- and extracellular signaling by anionic phospholipids. Biochem Biophys Res Commun. 2017 Jan 15;482(3):482-490. PMID: 28212735. PMCID: PMC5319735.

 

2016

Zemke AC, Kocak BR, Bomberger JM. Sodium Nitrite Inhibits Killing of Pseudomonas aeruginosa Biofilms by Ciprofloxacin. Antimicrob Agents Chemother. 2016 Dec 27;61(1):e00448-16. PMID: 27799207; PMCID: PMC5192113.

Stetten AZ, Moraca G, Corcoran TE, Tristram-Nagle S, Garoff S, Przybycien TM, Tilton RD. Enabling Marangoni flow at air-liquid interfaces through deposition of aerosolized lipid dispersions. J Colloid Interface Sci. 2016 Dec 15;484:270-278. PMID: 27623189; PMCID: PMC5075242.

Olonisakin TF, Li H, Xiong Z, Kochman EJ, Yu M, Qu Y, Hulver M, Kolls JK, St Croix C, Doi Y, Nguyen MH, Shanks RM, Mallampalli RK, Kagan VE, Ray A, Silverstein RL, Ray P, Lee JS. CD36 Provides Host Protection Against Klebsiella pneumoniae Intrapulmonary Infection by Enhancing Lipopolysaccharide Responsiveness and Macrophage Phagocytosis. J Infect Dis. 2016 Dec 15;214(12):1865-1875. PMID: 27683817; PMCID: PMC5142085.

Shrestha A, Hendricks MR, Bomberger JM, McClane BA. Bystander Host Cell Killing Effects of Clostridium perfringens Enterotoxin. mBio. 2016 Dec 13;7(6):e02015-16. PMID: 27965452; PMCID: PMC5156305.

Telles CJ, Decker SE, Motley WW, Peters AW, Mehr AP, Frizzell RA, Forrest JN Jr. Functional and molecular identification of a TASK-1 potassium channel regulating chloride secretion through CFTR channels in the shark rectal gland: implications for cystic fibrosis. Am J Physiol Cell Physiol. 2016 Dec 1;311(6):C884-C894. PMID: 27653983; PMCID: PMC5206301.

Kazmerski TM, Weiner DJ, Matisko J, Schachner D, Lerch W, May C, Maurer SH. Advance care planning in adolescents with cystic fibrosis: A quality improvement project Pediatr Pulmonol. 2016 Dec;51(12):1304-1310. PMID: 27749020.

Chen K, Eddens T, Trevejo-Nunez G, Way EE, Elsegeiny W, Ricks DM, Garg AV, Erb CJ, Bo M, Wang T, Chen W, Lee JS, Gaffen SL, Kolls JK. IL-17 Receptor Signaling in the Lung Epithelium Is Required for Mucosal Chemokine Gradients and Pulmonary Host Defense against K. pneumoniae. Cell Host Microbe. 2016 Nov 9;20(5):596-605. PMID: 27923703; PMCID: PMC5149406.

Melvin JA, Montelaro RC, Bomberger JM. Clinical potential of engineered cationic antimicrobial peptides against drug resistant biofilms. Expert Rev Anti Infect Ther. 2016 Nov;14(11):989-991. PMID: 27626708; PMCID: PMC5177990.

Muhlebach MS, Clancy JP, Heltshe SL, Ziady A, Kelley T, Accurso F, Pilewski J, Mayer-Hamblett N, Joseloff E, Sagel SD. Biomarkers for cystic fibrosis drug development J Cyst Fibros. 2016 Nov;15(6):714-723. PMID: 28215711; PMCID: PMC5321565.

Lakdawala SS, Fodor E, Subbarao K. Moving On Out: Transport and Packaging of Influenza Viral RNA into Virions. Annu Rev Virol. 2016 Sep 29;3(1):411-427. PMID: 27741407.

Moreira ÉA, Weber A, Bolte H, Kolesnikova L, Giese S, Lakdawala S, Beer M, Zimmer G, García-Sastre A, Schwemmle M, Juozapaitis M. A conserved influenza A virus nucleoprotein code controls specific viral genome packaging. Nat Commun. 2016 Sep 21;7:12861. PMID: 27650413; PMCID: PMC5035998.

Trevejo-Nunez G, Elsegeiny W, Conboy P, Chen K, Kolls JK. Critical Role of IL-22/IL22-RA1 Signaling in Pneumococcal Pneumonia. J Immunol. 2016 Sep 1;197(5):1877-83. PMID: 27456484; PMCID: PMC4992592.

Lashua LP, Melvin JA, Deslouches B, Pilewski JM, Montelaro RC, Bomberger JM. Engineered cationic antimicrobial peptide (eCAP) prevents Pseudomonas aeruginosa biofilm growth on airway epithelial cells. J Antimicrob Chemother. 2016 Aug;71(8):2200-7. PMID: 27231279; PMCID: PMC4954927.

Way EE, Trevejo-Nunez G, Kane LP, Steiner BH, Puri KD, Kolls JK, Chen K. Dose-Dependent Suppression of Cytokine production from T cells by a Novel Phosphoinositide 3-Kinase Delta Inhibitor. Sci Rep. 2016 Jul 27;6:30384. PMID: 27461849; PMCID: PMC4961957.

Chen K, Campfield BT, Wenzel SE, McAleer JP, Kreindler JL, Kurland G, Gopal R, Wang T, Chen W, Eddens T, Quinn KM, Myerburg MM, Horne WT, Lora JM, Albrecht BK, Pilewski JM, Kolls JK.  Antiinflammatory effects of bromodomain and extraterminal domain inhibition in cystic fibrosis lung inflammation. JCI Insight. 2016 Jul 21;1(11). PMID: 27517095. PMCID: PMC4978187.

Pinilla-Vera M, Xiong Z, Zhao Y, Zhao J, Donahoe MP, Barge S, Horne WT, Kolls JK, McVerry BJ, Birukova A, Tighe RM, Foster WM, Hollingsworth J, Ray A, Mallampalli R, Ray P, Lee JS. Full Spectrum of LPS Activation in Alveolar Macrophages of Healthy Volunteers by Whole Transcriptomic Profiling. PLoS One. 2016 Jul 19;11(7):e0159329. PMID: 27434537; PMCID: PMC4951018.

McAleer JP, Nguyen NL, Chen K, Kumar P, Ricks DM, Binnie M, Armentrout RA, Pociask DA, Hein A, Yu A, Vikram A, Bibby K, Umesaki Y, Rivera A, Sheppard D, Ouyang W, Hooper LV, Kolls JK. Pulmonary Th17 Antifungal Immunity Is Regulated by the Gut Microbiome. J Immunol. 2016 Jul 1;197(1):97-107. PMID: 27217583; PMCID: PMC4912941.

Deslouches B, Hasek ML, Craigo JK, Steckbeck JD, Montelaro RC. Comparative functional properties of engineered cationic antimicrobial peptides consisting exclusively of tryptophan and either lysine or arginine. J Med Microbiol. 2016 Jun;65(6):554-565. PMID: 27046192; PMCID: PMC5042116.

Kazmerski TM, Borrero S, Tuchman LK, Weiner DJ, Pilewski JM, Orenstein DM, Miller E. Provider and Patient Attitudes Regarding Sexual Health in Young Women With Cystic Fibrosis Pediatrics. 2016 Jun;137(6):e20154452. PMID: 27244858.

Melvin JA, Lashua LP, Kiedrowski MR, Yang G, Deslouches B, Montelaro RC, Bomberger JM. Simultaneous Antibiofilm and Antiviral Activities of an Engineered Antimicrobial Peptide during Virus-Bacterium Coinfection. mSphere. 2016 May 4;1(3):e00083-16. PMID: 27303744; PMCID: PMC4888888.

Locke LW, Myerburg MM, Weiner DJ, Markovetz MR, Parker RS, Muthukrishnan A, Weber L, Czachowski MR, Lacy RT, Pilewski JM, Corcoran TE. Pseudomonas infection and mucociliary and absorptive clearance in the cystic fibrosis lung Eur Respir J. 2016 May;47(5):1392-401. PMID: 27009167; PMCID: PMC5516211.

Hendricks MR, Bomberger JM. Digging through the Obstruction: Insight into the Epithelial Cell Response to Respiratory Virus Infection in Patients with Cystic Fibrosis. J Virol. 2016 Apr 14;90(9):4258-4261. PMID: 26865718; PMCID: PMC4836329.

Salomon JJ, Spahn S, Wang X, Füllekrug J, Bertrand CA, Mall MA. Generation and functional characterization of epithelial cells with stable expression of SLC26A9 Cl- channels. Am J Physiol Lung Cell Mol Physiol. 2016 Apr 1;310(7):L593-602. PMID: 26801567; PMCID: PMC4888553.

Ernst WL, Shome K, Wu CC, Gong X, Frizzell RA, Aridor M. VAMP-associated Proteins (VAP) as Receptors That Couple Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Proteostasis with Lipid Homeostasis. J Biol Chem. 2016 Mar 4;291(10):5206-20. PMID: 26740627; PMCID: PMC4777854.

Larsen MB, Hu J, Frizzell RA, Watkins SC. Simple image-based no-wash method for quantitative detection of surface expressed CFTR. Methods. 2016 Mar 1;96:40-45. PMID: 26361332; PMCID: PMC4773656.

Chen K, Kolls JK.  Innate Lymphoid Cells and Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2016 Feb 15;193(4):350-2. PMID: 26871668. PMCID: PMC4803088.

Hendricks MR, Lashua LP, Fischer DK, Flitter BA, Eichinger KM, Durbin JE, Sarkar SN, Coyne CB, Empey KM, Bomberger JM. Respiratory syncytial virus infection enhances Pseudomonas aeruginosa biofilm growth through dysregulation of nutritional immunity. Proc Natl Acad Sci U S A. 2016 Feb 9;113(6):1642-7. PMID: 26729873; PMCID: PMC4760822.

Veit G, Avramescu RG, Chiang AN, Houck SA, Cai Z, Peters KW, Hong JS, Pollard HB, Guggino WB, Balch WE, Skach WR, Cutting GR, Frizzell RA, Sheppard DN, Cyr DM, Sorscher EJ, Brodsky JL, Lukacs GL. From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations. Mol Biol Cell. 2016 Feb 1;27(3):424-33. PMID: 26823392; PMCID: PMC4751594.

Ahner A, Gong X, Frizzell RA. Divergent signaling via SUMO modification: potential for CFTR modulation Am J Physiol Cell Physiol. 2016 Feb 1;310(3):C175-80. PMID: 26582473; PMCID: PMC4838058.

Gong X, Ahner A, Roldan A, Lukacs GL, Thibodeau PH, Frizzell RA. Non-native Conformers of Cystic Fibrosis Transmembrane Conductance Regulator NBD1 Are Recognized by Hsp27 and Conjugated to SUMO-2 for Degradation J Biol Chem. 2016 Jan 22;291(4):2004-2017. PMID: 26627832; PMCID: PMC4722474.

Farinha CM, Swiatecka-Urban A, Brautigan DL, Jordan P. Regulatory Crosstalk by Protein Kinases on CFTR Trafficking and Activity. Front Chem. 2016 Jan 20;4:1. PMID: 26835446; PMCID: PMC4718993.

Kazmerski TM, Tuchman LK, Borrero S, Weiner D, Pilewski JM, Orenstein DM, Miller E. Cystic fibrosis program directors' attitudes toward sexual and reproductive health in young women with CF Pediatr Pulmonol. 2016 Jan;51(1):22-7. PMID: 26551521.

Taylor-Cousar J, Niknian M, Gilmartin G, Pilewski JM; VX11-770-901 investigators. Effect of ivacaftor in patients with advanced cystic fibrosis and a G551D-CFTR mutation: Safety and efficacy in an expanded access program in the United States J Cyst Fibros. 2016 Jan;15(1):116-22. PMID: 25682022.

Zou C, Synan MJ, Li J, Xiong S, Manni ML, Liu Y, Chen BB, Zhao Y, Shiva S, Tyurina YY, Jiang J, Lee JS, Das S, Ray A, Ray P, Kagan VE, Mallampalli RK. LPS impairs oxygen utilization in epithelia by triggering degradation of the mitochondrial enzyme Alcat1. J Cell Sci. 2016 Jan 1;129(1):51-64. PMID: 26604221; PMCID: PMC4732295.