The CFRC is comprised of 50 faculty members from ten departments, who provide research strengths in areas ranging from basic science to clinical investigations. Its members garner more than $13 M/yr in extramural grants and contracts to support our CF research efforts.

The Center's program support is derived from core center grants from the NIH and Cystic Fibrosis Foundation that primarily support core facilities and Pilot/Feasibility (P/F) Projects:

  • NIH-NIDDK P30 DK072506-04 "Basic and Translational Studies of Cystic Fibrosis"
  • Cystic Fibrosis Foundation RDP:R883-CR07 "Cystic Fibrosis Research Development Program"

Research Funds Available:

The CFRC has offered P/F grants to attract new investigators to CF research since 1997. Applications for these grants are submitted on an annual cycle with review in late spring and potential funding July 1. New applications are solicited via University-wide mailings three months prior (April 1).


Current and Past Pilot/Fesability Projects:

Pilot Start Date



Title of Pilot

June 1 2018

Vaughn Cooper


Response of the lung microbiome to commonly used inhaled antibiotics

October 1 2017

Carlos Camacho

Computational and
Systems Biology

Discovering novel inhibitors of the E3 ubiquitin ligase CHIP using a rational gemonic/structure-based screen

June 1 2017

Allison Morris/Barbara Methe


Microbiome-host interactions during cystic fibrosis pulmonary exaebations using multi-omics approaches

June 1 2016

Timothy Hand


Role of immune response to the intestinal microbiota in Cystic Fibrosis

June 1 2015

John Alcorn


The impact of CFTR dysfunction on epithelial host defense against S. aureus

June 1 2014

Agnes Urban


LMTK2 and TGF Beta Signaling in Human Airway Epithelial Cells

June 1 2013

Marcel Bruchez

CMU-Biological Sciences

Discovery of New Gene Targets for CF Therapies

June 1 2012

Ronald Montelaro


Engineered Cationic antimicrobial peptides (eCAP) for the treatment of viral and bacterial respiratory infections in CF patients

June 1 2012

Xinyu Lio


Decode the Viculence Signaling Network of Pathogenic Bacteria in Cystic Fibrosis Lung Infection

June 1 2011

Thomas Gilbert


Ex Vivo Model of Cystic Firbrosis

June 1 2011

Jennifer Bomberger


Pseudomanas-vial Co-infection in Cystic Fibrosis