John F. McDyer, MD

  • Professor
  • Department of Medicine
  • Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine

Education & Training

  • BS, Chemistry, St. Joseph's University, Philadelphia, 1986
  • MD, Thomas Jefferson Medical College, 1990
  • Residency, Internal Medicine, Barnes Hospital, Washington University, 1993
  • Fellowship, Allergy/Immunology, National Institute of Allergy and Infectious Diseases, 1998
  • Fellowship, Critical Care/Pulmonary Medicine, NIH Bethesda and Johns Hopkins University, 2002

Research Interest Summary

Immunobiology of Lung Transplantation

Research Interests

CMV infection remains the most common infection in lung transplant recipients (LTRs) and a major cause of morbidity and mortality. Dr McDyer’s research investigates T-bet, the T cell transcriptional factor to determine if it is necessary for protective CMV-specific immunity during acute and chronic CMV infection. To test this he uses both the murine CMV (MCMV) pulmonary infection model and the LTR cohort to study the role of T-bet in pulmonary and systemic CMV host defense and the development of protective T cell memory.